Performance characteristics of fluorescence endoscope in detection of head and neck cancers.

摘要: Laser-induced fluorescence endoscopy (LIFE) is a noninvasive method for detecting early cancers in hollow organs. A laser-induced endoscope that was designed lung imaging investigated its effectiveness comparison to white light (WLE) localizing head and neck cancers. total of 196 images from 98 sites 56 patients were graded into 5 levels normal definitely abnormal. cutoff level differentiate abnormal chosen receiver operating characteristic curve. On this basis, LIFE (sensitivity, 92.86%; specificity, 78.57%) observed be more effective reliable than WLE 67.86%; 70%) locating neoplastic foci precancerous lesions. Nevertheless, helpful presenting anatomic details. The reliability varied site site. It excelled examination the oropharynx 100%; 96.20%), but less lesions nasopharynx 66.70%; 75.00%). In standardizing test, interobserver variation assessed, good agreement image interpretation confirmed by statistical analysis. conclusion, found an tool