Effects of maternal deprivation and the duration of reunion time on rat pup ultrasonic vocalization responses to isolation: Possible implications for human infant studies

摘要: In a paradigm that may serve as translational model for maternal separation experiences of human infants in neonatal intensive care units, we examined how the duration reunion with dam influenced phenomenon potentiation ultrasonic vocalizations, which isolated rat pups increase rates vocalization following brief interactions dams. We report 12-13 day-old rats did not occur after reunions their anesthetized lasted longer than 15-min. However, 18 hr separation, given increased rate even long 3 hr. Using split-cage apparatus prevented physical contact, impact separations on was partially offset by experiencing olfactory and/or auditory stimuli mother. These results suggest maintaining partial sensory exposure during prolonged can reduce responses elicited subsequent separation.