Applicable advances in the molecular pathology of glioblastoma.

摘要: Comprising more than 80% of malignant brain tumors, glioma has proven to be a daunting cause mortality in vast majority the human population. Progressive and extensive research on substantially enhanced our understanding cell biology molecular pathology. Subtypes such as astrocytoma oligodendroglioma are currently grouped together into one pathological class, where they show many differences histology etiology. This indicates that it may beneficial consider new radical subclassification. Thus, we summarize recent developments glioblastoma multiforme (GBM) subtypes, immunohistochemical analyses useful for diagnoses biological evaluation therapeutic implications gliomas this review.