Cerebral resuscitation after traumatic brain injury and cardiopulmonary arrest in infants and children in the new millennium.

摘要: As outlined in Figure 1, it is likely that a series of interventions beginning the field and continuing through emergency department, ICU, rehabilitation center, possibly beyond, will be needed to optimize clinical outcome after severe TBI or asphyxial CA infants children. Despite many differences between these two important pediatric insults, therapies targeting neuronal death, either condition, need administered early insult, at injury scene. Even cerebral swelling, pathophysiologic derangement routinely treated PICU, almost certainly better prevented rather than treated. Finally, this review includes, for one first times, brief discussion additional horizons management patients with brain injury, namely, manipulation injured circuitry stimulation regeneration. Further research define pathobiology conditions bedside, understand optimal application contemporary therapies, develop apply novel therapies. The tools necessary carry out studies are materializing, although obstacles great. This difficult but challenge awaits further investigation by clinician-scientists neurointensive care.