Criteria for the development of biological reference materials

摘要: A review is presented of factors to be considered in the development biological reference materials. Some guidelines are offered regarding approaches generation varied materials required for analytical quality control. Major considerations such an endeavour goal undertaking and role final product, selection candidate materials, preparation, characterization certification. Selection should from those important commerce consumers, related various regulatory, clinical, environmental, research activities. They adequately represent different choices types foodstuffs, clinical environmental as soils, sewage sludges, plant animal tissues, interest regions world.