Design considerations for AIDS trials.

作者: David P. Byar , David A. Schoenfeld , Sylvan B. Green , David A. Amato , Roger Davis

DOI: 10.1056/NEJM199011083231912

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摘要: Statisticians and clinicians involved in the design conduct of trials new treatments for acquired immunodeficiency syndrome (AIDS) have realized that some traditional approaches to c...

参考文章(19)
David P. Byar, Assessing apparent treatment—covariate interactions in randomized clinical trials Statistics in Medicine. ,vol. 4, pp. 255- 263 ,(1985) , 10.1002/SIM.4780040304
A. R. Moss, Predicting who will progress to AIDS. BMJ. ,vol. 297, pp. 1067- 1068 ,(1988) , 10.1136/BMJ.297.6656.1067
Daniel J. Schaid, James N. Ingle, Sam Wieand, David L. Ahmann, A design for phase II testing of anticancer agents within a phase III clinical trial Controlled Clinical Trials. ,vol. 9, pp. 107- 118 ,(1988) , 10.1016/0197-2456(88)90032-3
John Mills, Mark A. Jacobson, James J. O'Donnell, Donna Cederberg, Gary N. Holland, Treatment of Cytomegalovirus Retinitis in Patients with AIDS Clinical Infectious Diseases. ,vol. 10, ,(1988) , 10.1093/CLINIDS/10.SUPPLEMENT_3.S522
Paul A. Volberding, Stephen W. Lagakos, Matthew A. Koch, Carla Pettinelli, Maureen W. Myers, David K. Booth, Henry H. Balfour, Richard C. Reichman, John A. Bartlett, Martin S. Hirsch, Robert L. Murphy, W. David Hardy, Ruy Soeiro, Margaret A. Fischl, John G. Bartlett, Thomas C. Merigan, Newton E. Hyslop, Douglas D. Richman, Fred T. Valentine, Lawrence Corey, , Zidovudine in Asymptomatic Human Immunodeficiency Virus Infection: A Controlled Trial in Persons with Fewer Than 500 CD4-Positive Cells per Cubic Millimeter The New England Journal of Medicine. ,vol. 322, pp. 941- 949 ,(1990) , 10.1056/NEJM199004053221401
R Yarchoan, H Mitsuya, R. Thomas, J. Pluda, N. Hartman, C. Perno, K. Marczyk, J. Allain, D. Johns, S Broder, In vivo activity against HIV and favorable toxicity profile of 2',3'-dideoxyinosine Science. ,vol. 245, pp. 412- 415 ,(1989) , 10.1126/SCIENCE.2502840
Henry W. Murray, James H. Godbold, Kenneth B. Jurica, Richard B. Roberts, Progression to AIDS in patients with lymphadenopathy or AIDS-related complex: reappraisal of risk and predictive factors The American Journal of Medicine. ,vol. 86, pp. 533- 538 ,(1989) , 10.1016/0002-9343(89)90380-X
PETER F. THALL, RICHARD SIMON, SUSAN S. ELLENBERG, Two-stage selection and testing designs for comparative clinical trials Biometrika. ,vol. 75, pp. 303- 310 ,(1988) , 10.1093/BIOMET/75.2.303
Sylvan B. Green, Susan S. Ellenberg, Dianne Finkelstein, Alan B. Forsythe, Laurence S. Freedman, Katherine Freeman, Myrto Lefkopoulou, David Schoenfeld, Rebecca P. Smith, Issues in the design of drug trials for AIDS Controlled Clinical Trials. ,vol. 11, pp. 80- 87 ,(1990) , 10.1016/0197-2456(90)90002-J
Alan G. Palestine, Clinical Aspects of Cytomegalovirus Retinitis Clinical Infectious Diseases. ,vol. 10, ,(1988) , 10.1093/CLINIDS/10.SUPPLEMENT_3.S515