Not nondipping but nocturnal blood pressure predicts left ventricular hypertrophy in the essential hypertensive patients: the Korean Ambulatory Blood Pressure multicenter observational study.

摘要: OBJECTIVE The aim of this study was to investigate whether nocturnal blood pressure (BP), established on the basis a single 24-h BP monitoring, is stronger predictor left ventricular hypertrophy (LVH) compared with nondipping status in essential hypertensive patients. METHODS A total 682 patients (mean age 56.1 ± 14.5 years, 50.7% women) who underwent echocardiography were enrolled. 'Nondipping status' defined as SBP fall less than 10% daytime mean SBP. LVH mass index exceeding 54.0 g/m men and 53.0 g/m women. Each patient categorized three groups according cardiovascular risk using 2007 European Society Hypertension/ Cardiology guidelines average or low, moderate, high very added risk. RESULTS Among participants, 184 (26.9%) showed echocardiography. proportion individuals profile 356 (52.1%). In multiple logistic regression analysis, 56 years at least [odds ratio (OR) 1.047, 95% confidence interval (CI) 1.031-1.063, P < 0.0001], female participants (OR 1.751, CI 1.172-2.616, P = 0.0062), BMI higher 24.6 kg/m 1.178, 1.110-1.250, P < 0.0001), smoking 1.793, 1.028-3.127, P = 0.0397), 127 mmHg 1.032, 1.009-1.055, P = 0.0059) significant independent predictors for whereas not 0.857, 0.481-1.528, P = 0.6013). CONCLUSION These findings suggest that rather may be better LVH, especially secondary tertiary referral hospital setting targeting relatively