Pulse Arrival Time Based Cuff-Less and 24-H Wearable Blood Pressure Monitoring and its Diagnostic Value in Hypertension

摘要: Ambulatory blood pressure monitoring (ABPM) has become an essential tool in the diagnosis and management of hypertension. Current standard ABPM devices use oscillometric cuff-based method which can cause physical discomfort to patients with repeated inflations deflations, especially during nighttime leading sleep disturbance. The ability measure ambulatory BP accurately comfortably without a cuff would be attractive. This study validated accuracy cuff-less approach for using pulse arrival time (PAT) measurements on both healthy hypertensive subjects potential management, is first its kind. wearable device was evaluated against 24 15 have known were taken from each subject over 24-h period by every 30 minutes daily activities. Mean daytime, calculated. Agreement between mean systolic (SBP) diastolic (DBP) measured two Bland-Altman plot ?1.4 ± 6.6 0.4 6.7 mmHg, respectively. Receiver operator characteristics (ROC) statistics used assess diagnostic detection above hypertension threshold (>120/70 mmHg). area under ROC curves 0.975/0.79 nighttime. results suggest that PAT-based accurate promising issue disturbances associated devices.