Gray matter abnormalities in pediatric mild traumatic brain injury.
作者： Andrew R. Mayer , Faith M. Hanlon , Josef M. Ling
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摘要: Abstract Pediatric mild traumatic brain injury (pmTBI) is the most prevalent neurological insult in children and associated with both acute chronic neuropsychiatric sequelae. However, little known about underlying pathophysiology changes gray matter diffusion atrophy from a prospective stand-point. Fifteen semi-acute pmTBI patients 15 well-matched healthy controls were evaluated clinical neuroimaging battery, subset of participants returning for second visit. Clinical measures included tests attention, processing speed, executive function, working memory, self-reported post-concussive symptoms. Measures (fractional anisotropy [FA]) also obtained cortical subcortical structures to characterize effects as function time. Patients exhibited decreased scores domains attention speed relative during stage, conjunction increased...
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