Rapid characterization of chemical constituents in Radix Tetrastigma, a functional herbal mixture, before and after metabolism and their antioxidant/antiproliferative activities

作者: Yong Sun , Yan Qin , Hongyan Li , Han Peng , Hongbing Chen

DOI: 10.1016/J.JFF.2015.07.009

关键词:

摘要: Radix Tetrastigma (RT), the roots of Tetrastigma hemsleyanum Diels et Gilg, is consumed as both functional food and traditional medicinal herb in China, but there is rare report on its bioactive components. In the present study, the total flavonoid contents (TFC) and antioxidant/antiproliferative activities of RT were evaluated, and the chemical constituents of RT and their metabolites of rat after oral administration were identified and quantified by UPLC-ESI-QTOF-MS/MS and UPLC-ESI-QqQ-MS/MS. The extract of RT exhibited high TFC …

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