Influence of 2-Br-α-ergocryptine on Serum Levels of Prolactin and the Estrous Cycle in Sheep

摘要: In a preliminary study 1 mg per day of 2-Br-a-ergocryptine (CB-154) was shown to be effective in reducing serum levels prolactin. second experiment CB-154 injected twice daily for 20 days, which included one complete estrous cycle, into 5 ewes. Serum luteinizing hormone, follicle-stimulating hormone and progesterone were not different between CB-154-injected control Prolactin reduced <0.5 ng⁄ml CB-154-treated ewes throughout the treatment period. ranged from 10 100 It concluded that luteal function as judged by regression marked corpora lutea, cycle length, or CB-154- treated These data suggest that: 1) very low prolactin are adequate insure normal function; 2) does play role regulation cycling sheep. (Endocrinology 94: 612, 1974)