Intermittent hypoxia-induced cardiorespiratory long-term facilitation: A new role for microglia.

摘要: Intermittent hypoxia induces plasticity in neural networks controlling breathing and cardiovascular function. Studies demonstrate that mechanisms causing cardiorespiratory rely on intracellular signalling pathways are activated by specific neurotransmitters. Peptides such as serotonin, PACAP orexin well-known for their physiological significance regulating the system. Their receptor counterparts present centres of brainstem medulla spinal cord. Microglial cells also important players inducing plasticity. The phenotype function microglial can change based state central nervous Here, we propose autonomic nuclei ventral relationship between neurotransmitters neurokines, neurons microglia determines overall