Controlling Nutritional Status (CONUT) score as a predictor of all-cause mortality in elderly hypertensive patients: a prospective follow-up study

作者: Xiaonan Sun , Leiming Luo , Xiaoqian Zhao , Ping Ye

DOI: 10.1136/BMJOPEN-2016-015649

关键词:

摘要: Objectives The aim of this study was to elucidate the impact nutritional status on survival per Controlling Nutritional Status (CONUT) score and Geriatric Risk Index (GNRI) in patients with hypertension over 80 years age. Design Prospective follow-up study. Participants A total 336 hypertensive old were included Outcome measures All-cause deaths recorded as Kaplan-Meier curves evaluate association between CONUT all-cause mortality at follow-up. Cox regression models used investigate prognostic value GNRI for 90-day period after admission. Results Hypertensive higher scores exhibited within 90 days admission (1.49%, 6.74%, 15.38%, respectively, χ 2 =30.92, p=0.000). Surviving had body mass index (24.25±3.05 vs 24.25±3.05, p=0.012), haemoglobin (123.78±17.05 115.07±20.42, p=0.040) albumin levels, well lower fasting blood glucose (6.90±2.48 8.24±3.51, p=0.010). Higher GRNI (99.42±6.55 95.69±7.77, p=0.002) (3.13±1.98 5.14±2.32) both indicated better status. that rates significantly worse high-CONUT group compared low-CONUT (χ 1 =13.372, p=0.001). an increase HR increasing risk (from normal moderate severe). HRs (95% CI) 3-month 1.458 (95% CI 1.102 1.911). In respiratory tract infection ‘other reason’ groups, only a sufficiently predictor (HR=1.284, 95% 1.013 1.740, p=0.020 HR=1.841, 95% CI 1.117 4.518, p=0.011). Receiver operating characteristic showed than 3.0 found predict sensitivity 77.8% specificity 64.7% (area under curve=0.778, p Conclusion assessed via is accurate postadmission. Evaluation may provide additional information patients.

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