Antimicrobial susceptibility of Shigella isolates in eight Asian countries, 2001-2004

摘要: BACKGROUND AND PURPOSE Shigellosis is a major health problem in developing countries, causing 91 million episodes and 414,000 deaths Asia annually. Because of increasing trends towards drug resistance, this study was undertaken to monitor local resistance patterns Shigella isolates from 8 Asian countries. METHODS Ninety eight collected centers countries July 2001 2004 were analyzed terms serogroup distribution antimicrobial susceptibility. RESULTS The most common flexneri (49/98, 50%), followed by sonnei (44/98, 45%). highest rate found for trimethoprim-sulfamethoxazole (81%), tetracycline (74%) ampicillin (53%). Overall, 76 (78%) multidrug-resistant strains; S. had higher multidrug than (74% vs 23%). Increasing ciprofloxacin ceftriaxone observed; approximately 10% 5% resistant ceftriaxone, respectively. Five ceftriaxone-non-susceptible strains (from Taiwan [3], Hong Kong [1] Philippines [1]) 10 ciprofloxacin-non-susceptible [2], [1], Korea Vietnam [4] Sri Lanka isolated. CONCLUSIONS High rates steady increases are serious pubic concerns Continuous monitoring among necessary.