Physical measures of recovery from anorexia nervosa during hospitalised re-feeding.

摘要: OBJECTIVE: To examine the relationship between weight gain, changes in body composition and physiological characteristics of fitness during recovery from anorexia nervosa. DESIGN: Longitudinal over eight weeks intensive inpatient re-feeding (Wk 0-8). SETTING: The London Hospital Medical College. SUBJECTS: Ten female patients who agreed to participate. Seven completed protocol. INTERVENTIONS: Dual-energy X-ray absorptiometry (dexa) skinfold thickness measures at Wk 0 8. Weekly peak expiratory flow rate cycle ergometry (several variables relating aerobic work recorded rest cycling low loads (0-60 W)). Blood samples for lactate potassium measures, taken 0, 4 8 only. RESULTS: (1) Body composition: Mean gain was 9.6 kg, dexa showing fat contribute 62% 54%, respectively. Both methods showed significant percentage with refeeding (P < 0.01 P 0.001, respectively), however there were differences results before 0.01) but not after = 0.2) refeeding. (2) Physiological function: Between 8, mean rose 85% predicted values, performance improved six subjects (three never reached 60 W load), respiratory exchange ratio (RER) fell 20 (both 0.05), oxygen pulse increased load values being well below normal. Oxygen uptake all line No seen heart or blood levels. CONCLUSIONS: Lean mass significantly methodological difference initial measurements requires further investigation. women had severely impaired function. Variables studied only slowly improving refeeding, capacity still