Metabolism and age

作者: N.W. Shock

DOI: 10.1016/0021-9681(55)90196-X

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摘要: Abstract In summary, it may be said that basal oxygen consumption of the total person diminishes gradually with increasing age. This decrement remains even when determinations are corrected for differences in body size, based on estimates surface area. all probability, metabolism per unit area females below males at advanced ages. However, calculations water content individual, age trends disappear, least males. Presumably this means reduction metabolism, age, is more result loss tissues and cells having relatively high rates than a reflection reduced metabolic activity remaining. Data resting uptake tissue slices offers little evidence decrease cell nucleus, exception bovine articular cartilage. Nor there good impaired thyroid function elderly people. Although slight 24-hour I131 aged people, best small sample which showed significant accumulation gradient subjects over 70. Thus, cannot assumed rate cellular necessarily With development new techniques, permit identification active principles from circulating blood tissues, should possible to resolve some these important problems.

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