Rapid synthesis of lipid nanoparticles containing hydrophobic inorganic nanoparticles.

作者: Jayesh A. Kulkarni , Yuen Yi C. Tam , Sam Chen , Ying K. Tam , Josh Zaifman

DOI: 10.1039/C7NR03272B

关键词:

摘要: … Cryo-TEM analysis of (A) LNP-GNP, and (B) LNP-QD … are large with high poly-dispersity indices (>200 nm with PDI … to the homogenous (PDI < 0.1) and scalable LNP–IONPs generated …

参考文章(39)
Sadao Hirota, Conchita Tros de Ilarduya, Lee G. Barron, Francis C. Szoka, Simple mixing device to reproducibly prepare cationic lipid-DNA complexes (lipoplexes) BioTechniques. ,vol. 27, pp. 286- 290 ,(1999) , 10.2144/99272BM16
Syed Z. Imam, Susan M. Lantz-McPeak, Elvis Cuevas, Hector Rosas-Hernandez, Serguei Liachenko, Yongbin Zhang, Sumit Sarkar, Jaivijay Ramu, Bonnie L. Robinson, Yvonne Jones, Bobby Gough, Merle G. Paule, Syed F. Ali, Zbigniew K. Binienda, Iron Oxide Nanoparticles Induce Dopaminergic Damage: In vitro Pathways and In Vivo Imaging Reveals Mechanism of Neuronal Damage Molecular Neurobiology. ,vol. 52, pp. 913- 926 ,(2015) , 10.1007/S12035-015-9259-2
Ruth Prassl, Frascione, Diwoky, Almer, Opriessnig, Vonach, Gradauer, Leitinger, Mangge, Stollberger, Ultrasmall superparamagnetic iron oxide (USPIO)-based liposomes as magnetic resonance imaging probes. International Journal of Nanomedicine. ,vol. 7, pp. 2349- 2359 ,(2012) , 10.2147/IJN.S30617
Yolanda Piñeiro, Zulema Vargas, José Rivas, Manuel Arturo López-Quintela, Iron Oxide Based Nanoparticles for Magnetic Hyperthermia Strategies in Biological Applications European Journal of Inorganic Chemistry. ,vol. 2015, pp. 4495- 4509 ,(2015) , 10.1002/EJIC.201500598
Lloyd B. Jeffs, Lorne R. Palmer, Ellen G. Ambegia, Cory Giesbrecht, Shannon Ewanick, Ian MacLachlan, A scalable, extrusion-free method for efficient liposomal encapsulation of plasmid DNA Pharmaceutical Research. ,vol. 22, pp. 362- 372 ,(2005) , 10.1007/S11095-004-1873-Z
Michael R. Rasch, Emma Rossinyol, Jose L. Hueso, Brian W. Goodfellow, Jordi Arbiol, Brian A. Korgel, Hydrophobic Gold Nanoparticle Self-Assembly with Phosphatidylcholine Lipid: Membrane-Loaded and Janus Vesicles Nano Letters. ,vol. 10, pp. 3733- 3739 ,(2010) , 10.1021/NL102387N
Y. Stein, G. Halperin, O. Stein, Biological stability of [3H]cholesteryl oleyl ether in cultured fibroblasts and intact rat FEBS Letters. ,vol. 111, pp. 104- 106 ,(1980) , 10.1016/0014-5793(80)80771-X
Igor V. Zhigaltsev, Nathan Belliveau, Ismail Hafez, Alex K. K. Leung, Jens Huft, Carl Hansen, Pieter R. Cullis, Bottom-Up Design and Synthesis of Limit Size Lipid Nanoparticle Systems with Aqueous and Triglyceride Cores Using Millisecond Microfluidic Mixing Langmuir. ,vol. 28, pp. 3633- 3640 ,(2012) , 10.1021/LA204833H
Rachela Popovtzer, Ashish Agrawal, Nicholas A. Kotov, Aron Popovtzer, James Balter, Thomas. E. Carey, Raoul Kopelman, Targeted gold nanoparticles enable molecular CT imaging of cancer. Nano Letters. ,vol. 8, pp. 4593- 4596 ,(2008) , 10.1021/NL8029114