Where there’s smoke, there’s atrial firing

摘要: Atrial fibrillation (AF) is the most common sustained arrhythmia in developed world, with many AF patients experiencing impaired quality of life, AF-related complications (eg, thromboembolic events, tachycardia-mediated cardiomyopathy), or a higher mortality rate. An aging population and advancements cardiovascular treatment suggest that incidence prevalence will continue to increase significant personal societal economic implications. In addition standard risk factors associated risk, recent evidence has suggested other clinical entities, such as obstructive sleep apnea, certain genetic phenotypes, smoking, might predispose its development. several large databases Atherosclerosis Risk Communities Study [ARIC], Rotterdam study, Shinken database study), smoking was an independent factor for development AF. Furthermore, some studies also predictor negative outcomes among patients. Cellular research suggests possible underlying mechanisms, which may account this association. However, investigations Danish Diet, Cancer Health Multifactor Primary Prevention Study) have failed detect association between AF, indicating need further investigation. Importantly, not always isolated activity, nonsmokers can be exposed second-hand smoke (SHS) their social professional environment. issue HeartRhythm, Dixit et al explore relationship SHS exposure early childhood later life. They base analysis on correlation responses questionnaire, obtained from enrolled Heart eHealth (an internet-based, longitudinal cohort study coordinated by University California–San Francisco), about gestational life tobacco subsequent The key finding