New insights on the association between the prostate cancer and the small DNA tumour virus, BK polyomavirus

作者: Mauro Tognon , Maurizio Provenzano

DOI: 10.1186/S12967-015-0754-Z

关键词:

摘要: In recent years the scientific literature in field of prostate carcinoma (PCa) pointed out on genetic heterogeneity and mutations occurring this tumour, while little attention was given to causes PCa onset, particular infectiuos agents. brief commentary, we wish point advancements done role human polyomavirus BK (BKPyV) development by harnessing both humoral cellular immune responses. Altogether, these new insights suggest that BKPyV is involved transforming activity during multistep process development. Although findings do not provide evidence for a causal relationship between development, additional investigations with novel techniques will help make it concrete event.

参考文章(12)
Xavier Etienne Keller, Piotr Kardas, Claudio Acevedo, Giovanni Sais, Cédric Poyet, Irina Banzola, Ashkan Mortezavi, Burkhardt Seifert, Tullio Sulser, Hans H. Hirsch, Maurizio Provenzano, Antibody response to BK polyomavirus as a prognostic biomarker and potential therapeutic target in prostate cancer. Oncotarget. ,vol. 6, pp. 6459- 6469 ,(2015) , 10.18632/ONCOTARGET.3363
T Mitchell, D E Neal, The genomic evolution of human prostate cancer. British Journal of Cancer. ,vol. 113, pp. 193- 198 ,(2015) , 10.1038/BJC.2015.234
Etienne Xavier Keller, Serena Delbue, Mauro Tognon, Maurizio Provenzano, Polyomavirus BK and prostate cancer: a complex interaction of potential clinical relevance Reviews in Medical Virology. ,vol. 25, pp. 366- 378 ,(2015) , 10.1002/RMV.1851
David C. Pallas, Lilian K. Shahrik, Bruce L. Martin, Stephen Jaspers, Thomas B. Miller, David L. Brautigan, Thomas M. Roberts, Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A. Cell. ,vol. 60, pp. 167- 176 ,(1990) , 10.1016/0092-8674(90)90726-U
Jin-Tang Dong, Prevalent mutations in prostate cancer Journal of Cellular Biochemistry. ,vol. 97, pp. 433- 447 ,(2006) , 10.1002/JCB.20696
M. Theile, Gabriele Grabowski, Mutagenic activity of BKV and JCV in human and other mammalian cells. Archives of Virology. ,vol. 113, pp. 221- 233 ,(1990) , 10.1007/BF01316675
Dweepanita Das, Rajal B Shah, Michael J Imperiale, Detection and expression of human BK virus sequences in neoplastic prostate tissues. Oncogene. ,vol. 23, pp. 7031- 7046 ,(2004) , 10.1038/SJ.ONC.1207920
Angelo M. De Marzo, Elizabeth A. Platz, Siobhan Sutcliffe, Jianfeng Xu, Henrik Grönberg, Charles G. Drake, Yasutomo Nakai, William B. Isaacs, William G. Nelson, Inflammation in prostate carcinogenesis Nature Reviews Cancer. ,vol. 7, pp. 256- 269 ,(2007) , 10.1038/NRC2090
Mauro Tognon, Alfredo Corallini, Fernanda Martini, Massimo Negrini, Giuseppe Barbanti-Brodano, Oncogenic transformation by BK virus and association with human tumors Oncogene. ,vol. 22, pp. 5192- 5200 ,(2003) , 10.1038/SJ.ONC.1206550
Serena Delbue, Pasquale Ferrante, Maurizio Provenzano, Polyomavirus BK and prostate cancer: an unworthy scientific effort? Delbue, Serena; Ferrante, Pasquale; Provenzano, Maurizio (2014). Polyomavirus BK and prostate cancer: an unworthy scientific effort? Oncoscience, 1(4):296-303.. ,vol. 1, pp. 296- 303 ,(2014) , 10.18632/ONCOSCIENCE.32