Mortality from acquired bullous diseases of skin in Canadian adults 2000–2007

摘要: Background  Bullous skin diseases are known to be associated with significant morbidity and mortality. There have been no studies on mortality from severe bullous in Canada. Methods  We used data the Statistics Canada website 2000 2007 for three major diseases: pemphigoid; pemphigus; toxic epidermal necrolysis (TEN). Crude age-standardized rates were calculated compared corresponding US rates. Linear regression was assess time trend effect of gender age rates. Results  During period eight years, there 115 deaths attributed pemphigoid, 84 pemphigus, 44 TEN. The crude annual rate highest pemphigoid (0.045 per 100,000), followed by pemphigus (0.033), TEN (0.017). None these conditions demonstrated trends over eight-year period, although a towards decreasing observed (P = 0.07). No difference observed, but advanced all conditions. Conclusion  Among diseases, is leading cause Canada. This contrast USA, where diseases. It not clear whether differences healthcare systems explain findings.