Karyotype analysis of teratocarcinomas and embryoid bodies of C3H mice.

作者: E. P. Evans , S. A. Iles

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摘要: Karyotype and capacity for differentiation were determined in four transplantable teratomas, their embryoid bodies, derived from C3H mouse embryos. An apparently normal karyotype was retained by one tumour subline that able to differentiate into a wide range of tissues, but some chromosomal alterations found the two tumours showed almost identical restrictions differentiation. Trisomy chromosome 11 shared all three restricted tumours; had similar length changes same (1 14) while third generally trisomic other chromosomes.

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