Attenuation of Noise in Ultrasensitive Signaling Cascades
作者： Mukund Thattai , Alexander van Oudenaarden
DOI: 10.1016/S0006-3495(02)75635-X
关键词:
摘要: … these fluctuation-bounded cascades can be used to attenuate the noise in an input signal, and we find the optimal cascade length required to achieve the best possible noise reduction. …
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J FERRELLJR, Tripping the switch fantastic: how a protein kinase cascade can convert graded inputs into switch-like outputs Trends in Biochemical Sciences. ,vol. 21, pp. 460- 466 ,(1996) , 10.1016/S0968-0004(96)20026-X
Attila Becskei, Luis Serrano, Engineering stability in gene networks by autoregulation Nature. ,vol. 405, pp. 590- 593 ,(2000) , 10.1038/35014651
Harley H McAdams, Adam Arkin, None, It’s a noisy business! Genetic regulation at the nanomolar scale Trends in Genetics. ,vol. 15, pp. 65- 69 ,(1999) , 10.1016/S0168-9525(98)01659-X
H. H. McAdams, A. Arkin, Stochastic mechanisms in gene expression Proceedings of the National Academy of Sciences of the United States of America. ,vol. 94, pp. 814- 819 ,(1997) , 10.1073/PNAS.94.3.814
P. B. Chock, E. R. Stadtman, Superiority of interconvertible enzyme cascades in metabolic regulation: analysis of monocyclic systems Proceedings of the National Academy of Sciences of the United States of America. ,vol. 74, pp. 2766- 2770 ,(1977) , 10.1073/PNAS.74.7.2766
Otto G. Berg, Johan Paulsson, Måns Ehrenberg, Fluctuations and Quality of Control in Biological Cells: Zero-Order Ultrasensitivity Reinvestigated Biophysical Journal. ,vol. 79, pp. 1228- 1236 ,(2000) , 10.1016/S0006-3495(00)76377-6
J. Hasty, J. Pradines, M. Dolnik, J. J. Collins, Noise-based switches and amplifiers for gene expression. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 97, pp. 2075- 2080 ,(2000) , 10.1073/PNAS.040411297
Ertugrul M. Ozbudak, Mukund Thattai, Iren Kurtser, Alan D. Grossman, Alexander van Oudenaarden, Regulation of noise in the expression of a single gene Nature Genetics. ,vol. 31, pp. 69- 73 ,(2002) , 10.1038/NG869
James E Ferrell Jr, Eric M Machleder, The Biochemical Basis of an All-or-None Cell Fate Switch in Xenopus Oocytes Science. ,vol. 280, pp. 895- 898 ,(1998) , 10.1126/SCIENCE.280.5365.895
M. Thattai, A. van Oudenaarden, Intrinsic noise in gene regulatory networks Proceedings of the National Academy of Sciences of the United States of America. ,vol. 98, pp. 8614- 8619 ,(2001) , 10.1073/PNAS.151588598