Inhibition of the recovery from potentially lethal damage by lonidamine.

摘要: Lonidamine [1-(2,4-dichlorobenzyl)-1-H-indazol-3-carboxylic acid] is shown to inhibit recovery from potentially lethal damage after exposure of cells X-rays, methyl methane sulfonate, or bleomycin and heat (43 degrees C, 1h). Inhibition most effective when the drug present before 10 25 mg l-1, a concentration readily achievable in vivo.