Time and spatial concentration profile inside a membrane by means of a memory formalism

摘要: Abstract In this note, the profile concentration of diffusing particles inside a membrane has been calculated on basis Fick diffusion equation modified by introducing memory formalism. highly heterogeneous systems, such as biological membranes, intrinsic structural complexity medium restricts applicability continuum models and suggests that parameters could depend at certain time or position what happens preceding times (diffusion with memory). Here, we deal two particular cases, glucose across an erythrocyte membrane, when both sides are assigned, permeation transport small molecular weight solute through artificial hydrogel polymeric membrane. However, present procedure can be easily extended to more general conditions. The knowledge within membranous structure, which is usually not experimentally accessible, completes description rather complex phenomenon structured confined also lead improvement in controlled drug-delivery systems.