Human metapneumovirus and community-acquired pneumonia in children.

作者: Pen Yi Lin , Tzou Yien Lin , Ya Ling Huang , Yhu Chering Huang , Kuo Chien Tsao

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摘要: Background Human metapneumovirus (hMPV) was first recognized in the Netherlands 2001 from nasopharyngeal aspirate samples and associated with respiratory tract illness pediatric population. This report of infections community-acquired pneumonia Taiwan. Methods A total 116 patients examined by reverse transcriptase polymerase chain reaction (RT-PCR). Other pathogens were also examined. The clinical characteristics laboratory data analyzed. Results Out patients, potential causative agents detected 95 (81.9%) patients. six human RT-PCR positive identified. All these had evidence coinfection bacteria (3 Streptococcus pneumoniae, 2 Mycoplasma 1 Chlamydia pneumoniae). Coinfection other viruses observed two cases (1 influenza A, parainfluenza type 3). age distribution seven to 11 years except for one patient who (Case 1). most common findings fever (6/6, 100%), cough (6/6,100%), rhinorrhea (5/6, 83.3%), rales 83.3%) wheezing (1/6, 16.7%). Chest radiographs revealed four lobar patches interstitial infiltrations. mean duration hospital stay 5.5 +/- 2.8 days. made a complete recovery. Conclusions hMPV identified 5.2% pneumonia. Our showed high rate infection, like viruses, may predispose secondary bacterial

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