Race, Childhood Insulin, Childhood Caloric Intake, and Class 3 Obesity at Age 24: 14-Year Prospective Study of Schoolgirls

作者: John A. Morrison , Charles J. Glueck , Stephen R. Daniels , Ping Wang

DOI: 10.1038/OBY.2011.126

关键词:

摘要: The prevalence of Class 3 obesity (BMI ≥40 kg/m2) has more than doubled in the past 25 years. In a 14-year prospective study from age 10 to 24 biracial schoolgirl cohort (293 black, 256 white), we assessed childhood correlates BMI at 24. Of 42 girls with 24, 36 (86%) were black. By logistic regression, significant explanatory variables included top decile waist circumference 11 (odds ratio (OR) 5.7, 95% confidence interval (CI) 2.3–13.9, P = 0.0002), ≥ Center for Disease Control (CDC) 2000 15% (OR 7.0, CI 2.5–19.3, and three-way interaction between race, insulin, average caloric intake 19 (for each unit increase, OR 1.7 1.3–2.2, 0.0003). Age BMI, circumference, predict young adulthood, facilitating identification high risk developing obesity.

参考文章(56)
Rebecca E Hasson, Tanja C Adam, Jaimie N Davis, Marc J Weigensberg, Emily E Ventura, Christianne J Lane, Christian K Roberts, Michael I Goran, None, Ethnic Differences in Insulin Action in Obese African-American and Latino Adolescents The Journal of Clinical Endocrinology and Metabolism. ,vol. 95, pp. 4048- 4051 ,(2010) , 10.1210/JC.2010-0018
C L Mosca, J A Marshall, G K Grunwald, M A Cornier, J Baxter, Insulin resistance as a modifier of the relationship between dietary fat intake and weight gain. International Journal of Obesity. ,vol. 28, pp. 803- 812 ,(2004) , 10.1038/SJ.IJO.0802621
M. Winiarska, D. Aregawi, G. Luo, J. Munjal, L. Sieve, P. Wang, C. J. Glueck, 74 METFORMIN-DIET AMELIORATES CORONARY HEART DISEASE RISK FACTORS AND FACILITATES RESUMPTION OF REGULAR MENSES IN ADOLESCENTS WITH POLYCYSTIC OVARY SYNDROME. Journal of Investigative Medicine. ,vol. 54, ,(2006) , 10.2310/6650.2005.X0015.152
Katherine M Flegal, Margaret D Carroll, Cynthia L Ogden, Clifford L Johnson, Prevalence and Trends in Obesity Among US Adults, 1999-2000 JAMA. ,vol. 288, pp. 1723- 1727 ,(2002) , 10.1001/JAMA.288.14.1723
C.J Glueck, Ping Wang, Robert Fontaine, Trent Tracy, Luann Sieve-Smith, Metformin to restore normal menses in oligo-amenorrheic teenage girls with polycystic ovary syndrome (PCOS). Journal of Adolescent Health. ,vol. 29, pp. 160- 169 ,(2001) , 10.1016/S1054-139X(01)00202-6
Gerald S. Berenson, Bhandaru Radhakrishnamurthy, Sathanur R. Srinivasan, Edward R. Dalferes, Xiaozhang Jiang, Racial (black-white) differences in insulin secretion and clearance in adolescents: the Bogalusa heart study. Pediatrics. ,vol. 97, pp. 357- 360 ,(1996)
D F Williamson, H S Kahn, T Byers, The 10-y incidence of obesity and major weight gain in black and white US women aged 30-55 y. The American Journal of Clinical Nutrition. ,vol. 53, ,(1991) , 10.1093/AJCN/53.6.1515S
Richard P. Troiano, Overweight Prevalence and Trends for Children and Adolescents Archives of Pediatrics & Adolescent Medicine. ,vol. 149, pp. 1085- 1091 ,(1995) , 10.1001/ARCHPEDI.1995.02170230039005