Plasmodium vivax treatments: what are we looking for?

作者: Ric N. Price , Nicholas M. Douglas , Nicholas M. Anstey , Lorenz von Seidlein

DOI: 10.1097/QCO.0B013E32834C61E3

关键词:

摘要: Purpose of Review For over 50 years the treatment Plasmodium vivax has relied on a combination chloroquine plus primaquine, but this strategy is under threat. Chloroquine efficacy now compromised across much endemic world and there are significant operational difficulties in deploying primaquine. We review recent advances P. chemotherapy that may influence future management neglected pathogen.

参考文章(76)
Hockwald Rs, Beutler E, Dern Rj, Clayman Cb, Alving As, Flanagan Cl, Arnold J, Potentiation of the curative action of primaquine in vivax malaria by quinine and chloroquine. Journal of Laboratory and Clinical Medicine. ,vol. 46, pp. 301- ,(1955)
J. Kevin Baird, Michael J. Bangs, Stephen L. Hoffman, Leslie C. Patchen, Purnomo, Hasan Basri, Budi Subianto, RESISTANCE TO CHLOROQUINE BY PLASMODIUM VIVAX IN IRIAN JAYA, INDONESIA American Journal of Tropical Medicine and Hygiene. ,vol. 44, pp. 547- 552 ,(1991) , 10.4269/AJTMH.1991.44.547
Te-Yu Hung, Timothy M. E. Davis, Kenneth F. Ilett, Harin Karunajeewa, Sean Hewitt, Mey Bouth Denis, Chiv Lim, Doung Socheat, Population pharmacokinetics of piperaquine in adults and children with uncomplicated falciparum or vivax malaria British Journal of Clinical Pharmacology. ,vol. 57, pp. 253- 262 ,(2003) , 10.1046/J.1365-2125.2003.02004.X
Harin Karunajeewa, Chiv Lim, Te-Yu Hung, Kenneth F. Ilett, Mey Bouth Denis, Doung Socheat, Timothy M. E. Davis, Safety evaluation of fixed combination piperaquine plus dihydroartemisinin (Artekin) in Cambodian children and adults with malaria. British Journal of Clinical Pharmacology. ,vol. 57, pp. 93- 99 ,(2003) , 10.1046/J.1365-2125.2003.01962.X
N. Dondorp, A., Nosten, F., Stepniewska, K., Day, N., & White, Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial. The Lancet. ,vol. 366, pp. 717- 725 ,(2005) , 10.1016/S0140-6736(05)67176-0
Dhanpat K. Kochar, Vikas Gupta, Vishal Saxena, Shilpi Garg, Ashish Das, Abhishek Kochar, Parmendra Sirohi, Sanjay K. Kochar, Mahesh P. Khatri, Severe Plasmodium vivax Malaria : A Report on Serial Cases from Bikaner in Northwestern India American Journal of Tropical Medicine and Hygiene. ,vol. 80, pp. 194- 198 ,(2009) , 10.4269/AJTMH.2009.80.194
Emiliana Tjitra, Joanne Baker, Sri Suprianto, Qin Cheng, Nicholas M. Anstey, Therapeutic Efficacies of Artesunate-Sulfadoxine-Pyrimethamine and Chloroquine-Sulfadoxine-Pyrimethamine in Vivax Malaria Pilot Studies: Relationship to Plasmodium vivax dhfr Mutations Antimicrobial Agents and Chemotherapy. ,vol. 46, pp. 3947- 3953 ,(2002) , 10.1128/AAC.46.12.3947-3953.2002
M. Mayxay, V. Thongpraseuth, M. Khanthavong, N. Lindegardh, M. Barends, S. Keola, T. Pongvongsa, S. Phompida, R. Phetsouvanh, K. Stepniewska, N. J. White, P. N. Newton, An open, randomized comparison of artesunate plus mefloquine vs. dihydroartemisinin–piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Lao People's Democratic Republic (Laos) Tropical Medicine & International Health. ,vol. 11, pp. 1157- 1165 ,(2006) , 10.1111/J.1365-3156.2006.01671.X
Harin A. Karunajeewa, Ivo Mueller, Michele Senn, Enmoore Lin, Irwin Law, P. Servina Gomorrai, Olive Oa, Suzanne Griffin, Kaye Kotab, Penias Suano, Nandao Tarongka, Alice Ura, Dulcie Lautu, Madhu Page-Sharp, Rina Wong, Sam Salman, Peter Siba, Kenneth F. Ilett, Timothy M.E. Davis, A Trial of Combination Antimalarial Therapies in Children from Papua New Guinea The New England Journal of Medicine. ,vol. 359, pp. 2545- 2557 ,(2008) , 10.1056/NEJMOA0804915
Christopher JM Whitty, Clare Chandler, Evelyn Ansah, Toby Leslie, Sarah G Staedke, None, Deployment of ACT antimalarials for treatment of malaria: challenges and opportunities Malaria Journal. ,vol. 7, pp. 1- 7 ,(2008) , 10.1186/1475-2875-7-S1-S7