Association of Krouse Classification for Sinonasal Inverted Papilloma With Recurrence: A Systematic Review and Meta-analysis

摘要: Importance The risk factors for the recurrence of sinonasal inverted papilloma are still unclear. Objective To investigate potential association between Krouse classification and rates papilloma. Data Sources EMBASE MEDLINE databases were searched period January 1, 1964, through September 30, 2016, using following search strategy: (paranasal sinuses [Medical Subject Headings (MeSH) terms] OR [all fields]) AND (inverted [MeSH fields] fields]). Study Selection inclusion criteria (1) studies including only no other forms papillomas, such as oncocytic papilloma; (2) minimum follow-up 1 year after surgery; (3) clear report cases (recurrence) controls according to system or deducible from full-text article. Literature was performed by 2 reviewers. Of 625 articles retrieved in literature, 97 reviewed. Observational cohort randomized controlled trials included, variables extracted articles: authors study, publication year, data, number (no recurrence) each 4 stages system. Extraction Synthesis Meta-analysis Studies Epidemiology (MOOSE) guidelines followed. Odds ratios (ORs) 95% CIs estimated, data included pooled a random-effects model. Main Outcomes Measures main outcome surgical removal stage Results Thirteen comprising 1787 patients analyzed. A significant increased (51%) highlighted T3 disease when compared with T2 (pooled OR, 1.51; CI, 1.09-2.09). No difference found T1 1.14; 0.63-2.04) T4 1.27; 0.72-2.26). Conclusions Relevance Inverted papillomas classified presented 51% higher likelihood recurrence. Head neck surgeons must be aware this planning performing surgery