Detection of Pneumococcal Capsular polysaccharide antigens by latex agglutination, counterimmunoelectrophoresis, and radioimmunoassay in middle ear exudates in acute otitis media.

摘要: The presence of pneumococcal antigen in middle ear exudates during acute otitis media was studied by latex agglutination and counterimmunoelectrophoresis. positive findings were confirmed radioimmunoassay. Latex gave a result 63% counterimmunoelectrophoresis 76% samples that grew Streptococcus pneumoniae. methods complementary; the detected one or both 88% these samples. Pneumococcal further 15% other pathogens 33% which no pathogenic bacteria recovered culture. distribution serotypes found immunochemical only corresponded to