摘要: The history of sperm immunology goes back to the turn century when immunogenicity spermatozoa was demonstrated, first in heterologous systems independently by Landsteiner (1899) and Metchnikoff shortly afterwards a homologous system Metalnikoff (1900). However, interest auto-immunity as possible cause infertility not evident until 1954, Rumke (1954) Wilson independent studies detected sperm-agglutinating -immobilising auto-antibodies sera few infertile men. In Wilson’s study auto-agglutination patients’ ejaculate lack penetration into cervical mucus observed. Indeed, it calls for admiration that main aspects immunological could be outlined with such precision studying only two patients!
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