作者: Stefania Staibano
DOI: 10.1007/978-94-007-7149-9_7
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摘要: Up to 70 % of newly diagnosed patients with advanced prostate cancer (PCa) will progress castration-resistant (CRPC) and, in most cases (from 50 %), develop hematogenous bone metastasis. Once PCa cells spread the skeleton, cancer-related death becomes inevitable, a burden more than 28,000 2012, United States (Semenas et al, Curr Drug Target, 13(10):1308–1323, 2012).