Detecting genetic effects on lipoprotein phenotypes in baboons: a review of methods and preliminary findings.
作者： Jean W. MacCluer , Candace M. Kammerer , John L. VandeBerg , Min-Lee Cheng , Glen E. Mott
DOI: 10.1007/BF00057446
关键词:
摘要: Statistical methods for detecting the contribution of major genes to quantitative phenotypes have been widely applied in human family studies. Some these are reviewed, and their application analysis an animal model a disease is described. Analysis lipoprotein concentrations pedigreed baboons provides evidence genetic effects on specific components that associated with reduced susceptibility atherosclerosis humans.
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