Proteomic pattern alterations of the cyanobacterium Synechocystis sp. PCC 6803 in response to cadmium, nickel and cobalt

摘要: Abstract Cyanobacteria represent the largest and most diverse group of prokaryotes capable performing oxygenic photosynthesis are frequently found in environments contaminated with heavy metals. Several studies have been performed these organisms order to better understand effects metals such as Zn, Cd, Cu, Ni Co. In Synechocystis sp. PCC 6803, genes involved Ni, Co, Cu Zn resistance reported. However, proteomic for identification proteins modulated by not carried out. present work, we analyzed pattern alterations cyanobacterium 6803 response Co Cd identify metabolic processes affected We show that some commonly regulated different metal ions, including ribulose1,5-bisphosphate carboxylase periplasmic iron-binding protein FutA2, while others, chaperones, were specifically induced each metal. also main carbon metabolism photosynthesis, since affect required correct functioning activities. Biological significance This is first report on profile wild type mutant strains Cd. identified responsive all three chaperones Our data supports previous suggest existence additional sensor systems