Sensitive determination of selenium by inductively coupled plasma mass spectrometry with flow injection and hydride generation in the presence of organic solvents

摘要: Parameters for selenium determination in inductively coupled plasma mass spectrometry (ICP-MS) by pneumatic nebulization and flow injection with hydride generation (FI-HG-ICP-MS) have been compared. The effect of organic solvents (methanol, ethanol, propanol, acetone acetonitrile) on the Se response has evaluated both sample introduction modes. Results show that addition alcohols leads to an important reduction polyatomic interferences (40Ar37Cl, 40Ar38Ar, 40Ar2H2) a 10-fold enhancement signal. solvent signal interference mechanisms are discussed. Under optimized operating conditions (NaBH4= 0.2%, pH1, methanol load = 6%), FI-HG-ICP-MS gives detection limits (3 sb) 1 pg 200 µl loop average RSD <2% under routine conditions. This system validated participation certification campaign throughout Europe inorganic selenium. It also applied direct dissolved SeIV natural estuarine waters.