The Sedimentable Components of Influenza Virus Propagated in Deembryonated Eggs

作者: Martin Hanig , Hans Bernkopf

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摘要: Summary and Conclusions The PR8 strain of type A influenza virus diluted to 10 −1 or −5 with Tyrode9s solution was propagated in deembryonated eggs. preparations obtained this manner were concentrated by ultracentrifugation, examined the analytical ultracentrifuge tested for hemagglutinating infectious capacities. It found that when inocula times low infectivity, moderately high capacity contained one major component sedimenting at approximately 480 S. Preparations also only component, but exhibited a sedimentation constant 630 S, comparable S preparations. has been concluded from these other data principle Type resides primarily heavy while hemagglutinative is distributed between light components.

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