Characterization of tetracycline-resistant strains of Ureaplasma urealyticum

摘要: Gel electrophoresis revealed no plasmids in cloned strains of Ureaplasma urealyticum for which minimal inhibitory concentration (MICs) tetracycline were greater than 64 mg/l. However, DNA from these hybridized with the tetM sequence Streptococcus agalactiae dot blot hybridization, whilst more-susceptible did not do so. Our results confirm and extend previous work, was associated resistance to antibiotics U. urealyticum. The examined this study isolated primarily western North America but included representatives Europe United Kingdom. Serotyping showed an increase serotype 9 determinant a decrease those 14 together shift biotype 2 cluster (P = less 0.02). To characterize identify alternative therapeutic basic research applications, 26 tetracycline-resistant tested against 25 diverse antimicrobial agents. All demonstrated in-vitro susceptibility rosaramicin resistant mg/l erythromycin. Only two 16 Most active isolates, low concentrations filipin unconventional agents such as flurofamide hydroquinone inhibited growth some strains.