Amyloids: Not Only Pathological Agents but Also Ordered Nanomaterials†

摘要: Amyloid fibers constitute one of the most abundant and important naturally occurring self-associated assemblies. A variety protein peptide molecules with various amino acid sequences form these highly stable well-organized assemblies under diverse conditions. These display phase states ranging from liquid crystals to rigid nanotubes. The potential applications supramolecular exceed those synthetic polymers since building blocks may introduce biological function in addition mechanical properties. Here we review structural characteristics amyloidal assemblies, their use as either natural or de novo designed sequences, range that have been demonstrated so far.