Cascade Multicomponent Synthesis of Indoles, Pyrazoles, and Pyridazinones by Functionalization of Alkenes

摘要: The development of multicomponent reactions for indole synthesis is demanding and has hardly been explored. present study describes the a novel multicomponent, cascade approach synthesis. Various substituted derivatives were obtained from simple reagents, such as unfunctionalized alkenes, diazonium salts, sodium triflinate, by using an established straightforward regioselective method. method based on radical trifluoromethylation alkenes entry into Fischer Besides synthesis, application reaction to pyrazoles pyridazinones described.