An epigenetic modifier triggers therapeutic immune responses against breast cancer.

Stephanie M Pyonteck, Leila Akkari, Alberto J Schuhmacher, Robert L Bowman, Lisa Sevenich, Daniela F Quail, Oakley C Olson, Marsha L Quick, Jason T Huse, Virginia Teijeiro, Manu Setty, Christina S Leslie, Yoko Oei, Alicia Pedraza, Jianan Zhang, Cameron W Brennan, James C Sutton, Eric C Holland, Dylan Daniel, Johanna A Joyce, CSF-1R inhibition alters macrophage polarization and blocks glioma progression Nature Medicine. ,vol. 19, pp. 1264- 1272 ,(2013) , 10.1038/NM.3337

Stephen L. Shiao, Brian Ruffell, David G. DeNardo, Bruce A. Faddegon, Catherine C. Park, Lisa M. Coussens, TH2-Polarized CD4+ T Cells and Macrophages Limit Efficacy of Radiotherapy Cancer immunology research. ,vol. 3, pp. 518- 525 ,(2015) , 10.1158/2326-6066.CIR-14-0232

Laura Senovilla, Fernando Aranda, Lorenzo Galluzzi, Guido Kroemer, Impact of myeloid cells on the efficacy of anticancer chemotherapy Current Opinion in Immunology. ,vol. 30, pp. 24- 31 ,(2014) , 10.1016/J.COI.2014.05.009

Stephen Mok, Richard C. Koya, Christopher Tsui, Jingying Xu, Lídia Robert, Lily Wu, Thomas G. Graeber, Brian L. West, Gideon Bollag, Antoni Ribas, Inhibition of CSF-1 receptor improves the antitumor efficacy of adoptive cell transfer immunotherapy Cancer Research. ,vol. 74, pp. 153- 161 ,(2014) , 10.1158/0008-5472.CAN-13-1816

Elaine Y. Lin, Andrew V. Nguyen, Robert G. Russell, Jeffrey W. Pollard, Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. Journal of Experimental Medicine. ,vol. 193, pp. 727- 740 ,(2001) , 10.1084/JEM.193.6.727

Guido Kroemer, Laura Senovilla, Lorenzo Galluzzi, Fabrice André, Laurence Zitvogel, Natural and therapy-induced immunosurveillance in breast cancer Nature Medicine. ,vol. 21, pp. 1128- 1138 ,(2015) , 10.1038/NM.3944

Aitziber Buqué, Norma Bloy, Fernando Aranda, Isabelle Cremer, Alexander Eggermont, Wolf Hervé Fridman, Jitka Fucikova, Jérôme Galon, Radek Spisek, Eric Tartour, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi, Trial Watch—Small molecules targeting the immunological tumor microenvironment for cancer therapy OncoImmunology. ,vol. 5, ,(2016) , 10.1080/2162402X.2016.1149674

Erika Vacchelli, Norma Bloy, Fernando Aranda, Aitziber Buqué, Isabelle Cremer, Sandra Demaria, Alexander Eggermont, Silvia Chiara Formenti, Wolf Hervé Fridman, Jitka Fucikova, Jérôme Galon, Radek Spisek, Eric Tartour, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi, Trial Watch: Immunotherapy plus radiation therapy for oncological indications OncoImmunology. ,vol. 5, ,(2016) , 10.1080/2162402X.2016.1214790

Alberto Mantovani, Massimo Locati, Macrophage Metabolism Shapes Angiogenesis in Tumors Cell Metabolism. ,vol. 24, pp. 653- 654 ,(2016) , 10.1016/J.CMET.2016.10.016

Alberto Mantovani, Federica Marchesi, Alberto Malesci, Luigi Laghi, Paola Allavena, Tumour-associated macrophages as treatment targets in oncology Nature Reviews Clinical Oncology. ,vol. 14, pp. 399- 416 ,(2017) , 10.1038/NRCLINONC.2016.217