摘要: Schizophrenia and bipolar disorder have a largely unknown pathophysiology etiology, but they are highly heritable. Although linkage association studies identified series of chromosomal regions likely to contain susceptibility genes, progress in identifying causative genes has been disappointing. However, rapid technological advances beginning lead new insights. Systematic genome-wide follow-up reported significant findings common variants for schizophrenia disorder. The risk conferred by individual is small, some confer both disorders. In addition, recent rare, large structural (copy number variants) that greater schizophrenia. This review summarizes developments genetic research into disorder, discusses possible future directions this field.
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