Mechanical ventilation for the lung transplant recipient

摘要: Mechanical ventilation (MV) is an important aspect in the intraoperative and early postoperative management of lung transplant (LTx) recipients. There are no randomized-controlled trials LTx recipient MV strategies; however, there center experiences international survey studies reported. The main complication primary graft dysfunction (PGD), which similar to adult respiratory distress syndrome (ARDS). We aim summarize information pertinent LTx-MV, as well PGD, ARDS, MV, synthesize these available data into recommendations. Based on evidence, we recommend lung-protective with low tidal volumes (≤6 mL/kg predicted body weight [PBW]) positive end-expiratory pressure for recipient. In our opinion, strategy should be based donor characteristics (donor PBW a parameter actual allograft size), rather than characteristics; this characteristics-based protective indirect evidence requires validation prospective clinical studies.