Mechanical ventilation after lung transplantation

摘要: Abstract Introduction To explore the hypothesis that early ventilation strategies influence clinical outcomes in lung transplantation, we have examined our routine practices terms of tidal volumes (Vt) and inflation pressures. Methods A total 124 bilateral transplants between 2010 2013 were retrospectively assigned to low (  8 mL/kg) Vt groups based on characteristics during first 6 hours after surgery. Those same patients also stratified low-pressure 2 O) high-pressure (≥ 25 cm H groups. Results Eighty percent ventilated using pressure control mode. Low, medium, high applied 10%, 43%, 47% patients, respectively. After correcting for requiring extracorporeal support, there was no difference short-term midterm among different Low pressures 61% who had a shorter length intensive care unit stay (5 vs 12 days; P = .012), higher forced expiratory volume 1 second at 3 months (77.8% 60.3%; .008). Conclusion has not been fully adopted practice. Ventilation with pressures, but Vt, significantly associated poorer transplantation.