Expression of the C-Fos Gene During Differentiation

摘要: Retroviruses cause tumors in experimental animals via a number of diverse mechanisms. One group viruses induces transformation by introduction viral gene (v-onc) derived from normal cellular (c-onc) (1–3). In general, acquisition the c-onc is accompanied various alterations, including single base changes and deletions, fusions with other or genes (4). The oncogenes which have been isolated about twenty, majority are, are related to, encoding bonafide protein tyrosine kinases (2,4,5). function another genes, fos, myb, myc ski, not determined, but their localization nucleus suggests that they may play role control expression.