Complete Nucleotide Sequences of 93-kb and 3.3-kb Plasmids of an Enterohemorrhagic Escherichia coli O157:H7 Derived from Sakai Outbreak
作者： Kozo Makino , Kazuo Ishii , Teruo Yasunaga , Masahiro Hattori , Katsushi Yokoyama
DOI: 10.1093/DNARES/5.1.1
关键词:
摘要: Enterohemorrhagic Escherichia coli (EHEC) O157:H7, derived from an outbreak in Sakai city, Japan 1996, possesses two kinds of plasmids: a 93-kb plasmid termed pO157, found clinical EHEC isolates world-wide and 3.3-kb pOSAK1, prevalent strains isolated Japan. Complete nucleotide sequences both plasmids have been determined, the putative functions encoded proteins cis-acting DNA analyzed. pO157 shares strikingly similar genes with F-factor transmissible drug-resistant R100 for replication, copy number control, segregation, conjugative stable maintenance host, although it is defective transfer by conjugation due to truncation deletion required sequences. In addition, encodes several implicated pathogenicity such as hemolysin (HlyA), catalase-peroxidase (KatP), serine protease (EspP) type II secretion system. pOSAK1 ColE1-like replication system, sequence extremely that plasmid, NTP16, Salmonella typhimurium except lacks drug resistance transposons.
oup.com
elsevier.com
oxfordjournals.org
archives-ouvertes.fr
sci-hub.se 参考文章(53)
K. Gerdes, F.W. Bech, S.T. Jørgensen, A. Løbner-Olesen, P.B. Rasmussen, T. Atlung, L. Boe, O. Karlstrom, S. Molin, K. von Meyenburg, Mechanism of postsegregational killing by the hok gene product of the parB system of plasmid R1 and its homology with the relF gene product of the E. coli relB operon. The EMBO Journal. ,vol. 5, pp. 2023- 2029 ,(1986) , 10.1002/J.1460-2075.1986.TB04459.X
Thomas Ryder, Jonathan Rosen, Karen Armstrong, Dan Davison, Eiichi Ohtsubo, Hisako Ohtsubo, DISSECTION OF THE REPLICATION REGION CONTROLLING INCOMPATIBILITY, COPY NUMBER, AND INITIATION OF DNA SYNTHESIS IN THE RESISTANCE PLASMIDS, R100 AND R1 The Initiation of Dna Replication. pp. 91- 111 ,(1981) , 10.1016/B978-0-12-583580-0.50013-3
M B Cohen, R A Giannella, Hemorrhagic colitis associated with Escherichia coli O157:H7. Advances in internal medicine. ,vol. 37, pp. 173- 195 ,(1992)
Takeyoshi Miki, Zong-Tsang Chang, Tadao Horiuchi, Control of cell division by sex factor F in Escherichia coli: II. Identification of genes for inhibitor protein and trigger protein on the 42.84–43.6 F segment Journal of Molecular Biology. ,vol. 174, pp. 627- 646 ,(1984) , 10.1016/0022-2836(84)90087-1
J H Crosa, J F Perez-Casal, Novel incompatibility and partition loci for the REPI replication region of plasmid ColV-K30. Journal of Bacteriology. ,vol. 169, pp. 5078- 5086 ,(1987) , 10.1128/JB.169.11.5078-5086.1987
Takeyoshi Miki, Katsuji Yoshioka, Tadao Horiuchi, Control of cell division by sex factor F in Escherichia coli: I. The 42.84–43.6 F segment couples cell division of the host bacteria with replication of plasmid DNA Journal of Molecular Biology. ,vol. 174, pp. 605- 625 ,(1984) , 10.1016/0022-2836(84)90086-X
Y Yoshioka, H Ohtsubo, E Ohtsubo, Repressor gene finO in plasmids R100 and F: constitutive transfer of plasmid F is caused by insertion of IS3 into F finO. Journal of Bacteriology. ,vol. 169, pp. 619- 623 ,(1987) , 10.1128/JB.169.2.619-623.1987
L S Frost, K Ippen-Ihler, R A Skurray, Analysis of the sequence and gene products of the transfer region of the F sex factor. Microbiological Research. ,vol. 58, pp. 162- 210 ,(1994) , 10.1128/MR.58.2.162-210.1994
Patricia M. Griffin, Robert V. Tauxe, The Epidemiology of Infections Caused by Escherichia coli O157: H7, Other Enterohemorrhagic E. coli, and the Associated Hemolytic Uremic Syndrome Epidemiologic Reviews. ,vol. 13, pp. 60- 98 ,(1991) , 10.1093/OXFORDJOURNALS.EPIREV.A036079
Cecil W. Harkey, Keith D. Everiss, Kenneth M. Peterson, Isolation and characterization of a Vibrio cholerae gene (tagA) that encodes a ToxR-regulated lipoprotein Gene. ,vol. 153, pp. 81- 84 ,(1995) , 10.1016/0378-1119(94)00811-6