The threshold of amylin-induced anorexia is lower in chicks selected for low compared to high juvenile body weight.

作者: Mark A. Cline , Wint Nandar , Christie Bowden , Wendy Calchary , Marissa L. Smith

DOI: 10.1016/J.BBR.2009.12.032

关键词:

摘要: Chicks that have undergone long-term selection for low body weight responded to intracerebroventricular amylin injection with reduced food intake at a dose considerably lower and greater magnitude suppression than those selected high weight. Behaviors unrelated ingestion were not affected. These data support the thesis of correlated system responses or weight, possible implications other species.

参考文章(25)
C. J. Billington, A. S. Levine, J. E. Morley, Are peptides truly satiety agents? A method of testing for neurohumoral satiety effects American Journal of Physiology-regulatory Integrative and Comparative Physiology. ,vol. 245, ,(1983) , 10.1152/AJPREGU.1983.245.6.R920
Giuseppe Clementi, Lina Busa, Ernesto de Bernardis, Agatina Prato, Filippo Drago, Effects of centrally injected amylin on sexual behavior of male rats Peptides. ,vol. 20, pp. 379- 382 ,(1999) , 10.1016/S0196-9781(98)00166-1
E Del Prete, B Schade, T Riediger, T.A Lutz, E Scharrer, Effects of amylin and salmon calcitonin on feeding and drinking behavior in pygmy goats Physiology & Behavior. ,vol. 75, pp. 593- 599 ,(2002) , 10.1016/S0031-9384(02)00655-8
M. Furuse, R. Ando, T. Bungo, M. Shimojo, Y. Masuda, Intracerebroventricular injection of orexins does not stimulate food intake in neonatal chicks British Poultry Science. ,vol. 40, pp. 698- 700 ,(1999) , 10.1080/00071669987115
D.Michael Denbow, Sharonda Meade, Adam Robertson, John P McMurtry, Mark Richards, Chris Ashwell, Leptin-induced decrease in food intake in chickens. Physiology & Behavior. ,vol. 69, pp. 359- 362 ,(2000) , 10.1016/S0031-9384(99)00258-9
Joel L. Davis, David T. Masuoka, Lauren K. Gerbrandt, Arthur Cherkin, Autoradiographic distribution of L-proline in chicks after intracerebral injection Physiology & Behavior. ,vol. 22, pp. 693- 695 ,(1979) , 10.1016/0031-9384(79)90233-6
J. A. DEUTSCH, W. T. HARDY, Cholecystokinin produces bait shyness in rats Nature. ,vol. 266, pp. 196- 196 ,(1977) , 10.1038/266196A0
Thomas A Lutz, Markus Senn, Janine Althaus, Elvira Del Prete, Felix Ehrensperger, Erwin Scharrer, Lesion of the Area Postrema/Nucleus of the Solitary Tract (AP/NTS) Attenuates the Anorectic Effects of Amylin and Calcitonin Gene-Related Peptide (CGRP) in Rats Peptides. ,vol. 19, pp. 309- 317 ,(1998) , 10.1016/S0196-9781(97)00292-1
Mark A. Cline, Wint Nandar, Marissa L. Smith, Bryan H. Pittman, Mathew Kelly, J. Orion Rogers, Amylin causes anorexigenic effects via the hypothalamus and brain stem in chicks. Regulatory Peptides. ,vol. 146, pp. 140- 146 ,(2008) , 10.1016/J.REGPEP.2007.09.003
I. A. Macdonald, T. A. Stubbs, A. C. Perkins, P. E. Blackshaw, C. Moyses, R. B. Tattersall, M.-F. Kong, P. King, Infusion of pramlintide, a human amylin analogue, delays gastric emptying in men with IDDM Diabetologia. ,vol. 40, pp. 82- 88 ,(1997) , 10.1007/S001250050646