Comparative Study of 5'-Nucleotidase Test in Various Liver Diseases.
作者： Mohd Azam Hyder , Marghoob Hasan , Abdelmarouf Mohieldein
DOI: 10.7860/JCDR/2016/12754.7163
关键词:
摘要: Introduction The liver regulates many important metabolic functions. 5'-nucleotidase activity is increased in obstructive jaundice, parenchymal disease, and hepatic metastases. Aim This study was conducted to assess the serum levels of on patients with viral hepatitis, alcoholic diseases cirrhosis, moreover make comparison degree biliary involvement. Materials methods A total 60 male subjects (15 healthy controls 45 case subjects) were enrolled, aged between 30 -50 years, each group consisted 15 age-matched suffering disease (more than 10 years.) cirrhosis. Serum analyzed as per standard laboratory procedure. Results significantly raised cirrhosis patients. being 35.2±8.43, 29.87±3.94, 24.07± 4.33 respectively compared control (11±3.42) U/L. Conclusion showed elevations mean value three fold 2.5 folds elevation two subjects.
sci-hub.st 参考文章(12)
Avinash A K. Math, Prakash B. Desai, Shivaraj Gowda, Vinayak V. Hull, Shruthi S. Kulkarni, Sonal N. Vernekar, A review on laboratory liver function tests The Pan African medical journal. ,vol. 3, pp. 17- 17 ,(2009)
Miya Fukano, Shigeru Amano, Fumitada Hazama, Shiro Hosoda, 5'-Nucleotidase activities in sera and liver tissues of viral hepatitis patients. Gastroenterologia Japonica. ,vol. 25, pp. 199- 205 ,(1990) , 10.1007/BF02776816
Yugal Kumar, G. Sahoo, Prediction of different types of liver diseases using rule based classification model Technology and Health Care. ,vol. 21, pp. 417- 432 ,(2013) , 10.3233/THC-130742
Franca Pagani, Mauro Panteghini, 5′-Nucleotidase in the Detection of Increased Activity of the Liver Form of Alkaline Phosphatase in Serum Clinical Chemistry. ,vol. 47, pp. 2046- 2048 ,(2001) , 10.1093/CLINCHEM/47.11.2046
K. Pratibha, Usha Anand, Rajni Agarwal, Serum adenosine deaminase, 5' nucleotidase and malondialdehyde in acute infective hepatitis. Indian Journal of Clinical Biochemistry. ,vol. 19, pp. 128- 131 ,(2004) , 10.1007/BF02894271
B. R. Thapa, Anuj Walia, Liver function tests and their interpretation Indian Journal of Pediatrics. ,vol. 74, pp. 663- 671 ,(2007) , 10.1007/S12098-007-0118-7
Paul L. Wolf, Biochemical diagnosis of liver disease Indian Journal of Clinical Biochemistry. ,vol. 14, pp. 59- 90 ,(1999) , 10.1007/BF02869152
K. Smith, H. H. Varon, G. J. Race, D. L. Paulson, H. C. Urschel, J. T. Mallams, Serum 5′-nucleotidase in patients with tumor in the liver Cancer. ,vol. 19, pp. 1281- 1285 ,(1966) , 10.1002/1097-0142(196609)19:9<1281::AID-CNCR2820190914>3.0.CO;2-0
D. S. Raghavendra, Shrinivas B. Rao, Studies on some serum enzyme levels in various liver diseases. Indian Journal of Clinical Biochemistry. ,vol. 15, pp. 48- 51 ,(2000) , 10.1007/BF02873548
Shirish Barve, Craig J McClain, Christian Mendez, Daniell Hill, Luis S Marsano, Diagnosis and treatment of alcoholic liver disease and its complications. Alcohol Research & Health. ,vol. 27, pp. 247- 256 ,(2003)