Serum adenosine deaminase and cytidine deaminase activities in patients with systemic lupus erythematosus.
作者： Seyithan Taysi , M. Fevzi Polat , Refik Ali Sari , Ebubekir Bakan
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摘要: We evaluated serum total adenosine deaminase, its isoenzymes deaminase-1 and deaminase-2, cytidine deaminase activities in 24 patients with active systemic lupus erythematosus, 26 healthy control subjects, found the means±SD values to be 21.38±5.96 IU/1, 3.74±2.12 IU/l, 17.72±5.02 IU/l 17.89±4.62 respectively patients, 14.97±4.71 4.01±1.35 10.91±3.91 7.39±3.97 subjects. When compared controls, deaminase-2 levels were significantly higher (p 0.05). The increased may of macrophage origin. It closely correlated clinical signs erythematosus. membranes polymorphonuclear neutrophils damaged, released into serum. In conclusion, serve as useful indicators for evaluating disease activity
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