Clinical impact of chemotherapy-induced thrombocytopenia in patients with gynecologic cancer.

作者: G L Goldberg , D G Gibbon , H O Smith , C DeVictoria , C D Runowicz

DOI: 10.1200/JCO.1994.12.11.2317

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摘要: PURPOSE AND METHODS This retrospective analysis of 501 patients with gynecologic cancer treated with chemotherapy evaluates the relationship between platelet count and clinical bleeding, as well as the clinical effects of platelet transfusion therapy. Thrombocytopenic patients were divided into six groups according to platelet counts, and major or minor bleeding manifestations were documented. Thrombocytopenia was defined as a platelet count less than 100,000/microL. RESULTS Thrombocytopenia occurred in 182 …

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