The democratization of gene editing: Insights from site-specific cleavage and double-strand break repair.

作者: Maria Jasin , James E. Haber

DOI: 10.1016/J.DNAREP.2016.05.001

关键词:

摘要: … BIR is prevented by deletion of … cleavage are based on structural determinations of the Cas9 nuclease with guide RNA and the DNA target with the premise that reducing non-specific …

参考文章(181)
W. M. Hicks, M. Yamaguchi, J. E. Haber, Real-time analysis of double-strand DNA break repair by homologous recombination. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 108, pp. 3108- 3115 ,(2011) , 10.1073/PNAS.1019660108
Catherine E. Smith, Bertrand Llorente, Lorraine S. Symington, Template switching during break-induced replication Nature. ,vol. 447, pp. 102- 105 ,(2007) , 10.1038/NATURE05723
Michael R Lieber, Yunmei Ma, Ulrich Pannicke, Klaus Schwarz, The mechanism of vertebrate nonhomologous DNA end joining and its role in V(D)J recombination. DNA Repair. ,vol. 3, pp. 817- 826 ,(2004) , 10.1016/J.DNAREP.2004.03.015
John R. Lydeard, Suvi Jain, Miyuki Yamaguchi, James E. Haber, Break-induced replication and telomerase-independent telomere maintenance require Pol32 Nature. ,vol. 448, pp. 820- 823 ,(2007) , 10.1038/NATURE06047
G. Gasiunas, R. Barrangou, P. Horvath, V. Siksnys, Cas9–crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria Proceedings of the National Academy of Sciences of the United States of America. ,vol. 109, pp. 15539- 15540 ,(2012) , 10.1073/PNAS.1208507109
Satoru Nogami, Tomoyuki Fukuda, Yuri Nagai, Shizu Yabe, Masako Sugiura, Ryuta Mizutani, Yoshinori Satow, Yasuhiro Anraku, Yoshikazu Ohya, Homing at an extragenic locus mediated by VDE (PI‐SceI) in Saccharomyces cerevisiae Yeast. ,vol. 19, pp. 773- 782 ,(2002) , 10.1002/YEA.872
A. Hinnen, J. B. Hicks, G. R. Fink, Transformation of yeast Proceedings of the National Academy of Sciences of the United States of America. ,vol. 75, pp. 1929- 1933 ,(1978) , 10.1073/PNAS.75.4.1929
Ying Shen, Pavan Nandi, Matthew B. Taylor, Samantha Stuckey, Hershel P. Bhadsavle, Bernard Weiss, Francesca Storici, RNA-driven genetic changes in bacteria and in human cells Mutation Research. ,vol. 717, pp. 91- 98 ,(2011) , 10.1016/J.MRFMMM.2011.03.016
Kevin Brick, Fatima Smagulova, Pavel Khil, R. Daniel Camerini-Otero, Galina V. Petukhova, Genetic recombination is directed away from functional genomic elements in mice Nature. ,vol. 485, pp. 642- 645 ,(2012) , 10.1038/NATURE11089
Ana Peciña, Kathleen N. Smith, Christine Mézard, Hajime Murakami, Kunihiro Ohta, Alain Nicolas, Targeted Stimulation of Meiotic Recombination Cell. ,vol. 111, pp. 173- 184 ,(2002) , 10.1016/S0092-8674(02)01002-4