Patterned Co-culture of Live Cells on a Microchip by Photocrosslinking with Benzophenone
作者： Kiichi SATO , Sayaka KIKUCHI , Eri YOSHIDA , Reina ISHII , Naoki SASAKI
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摘要: The patterned coculture of different types living cells in a microfluidic device is crucial for the analysis cellular interactions and cell-cell communication. In present study, cell patterning was achieved by photocrosslinking benzophenone derivatives channel. Optimization UV irradiation conditions enabled successful fixation live cells. addition, co-culture non-adherent K562 adherent RF-6A successive rounds patterning. approach expected to be useful development vitro methods studying signaling.
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